Managing Drug Interactions That Can Reduce Levothyroxine Efficacy

نویسندگان

  • Lori B. Arnold
  • PharmD
  • Lauren M. Czosnowski
چکیده

Levothyroxine is one of the most commonly prescribed medications for the treatment of persons with hypothyroidism and the suppression of thyroid neoplasms.1 Most persons with hypothyroidism require lifelong therapy with levothyroxine. The absorption of levothyroxine after oral administration is about 80%.1 Certain drugs and dietary components2,3 can interfere with the bioavailability of levothyroxine. Drugs include calcium carbonate,4-9 iron salts,10-12 and aluminum13-15 and magnesium-containing15 antacids.

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تاریخ انتشار 2017